Each patient is unique, and we are committed to building trusting relationships by offering individual fertility treatment solutions best suited for couples and single women. Our laboratories are equipped with the latest technology to ensure the best conditions for the culturing of gametes and embryos. We have extensive experience in freezing and preserving gametes.
Fertilization procedure outside the body (in vitro fertilization). The fertilization of the eggs and the first days of embryo development take place under laboratory conditions. In vitro fertilization usually requires stimulation of the ovaries before the procedure. If the sperm count of the male is normal, the eggs are fertilized using the traditional IVF method. In the case of male factor infertility, the ICSI (intracytoplasmic sperm injection) method is used. In vitro fertilization and its success rate varies for each individual and depends on the causes of infertility. On average, approximately 30% of procedures result in a successful pregnancy.
IUI (intrauterine insemination) is a procedure where the sperm is placed into the uterus during ovulation using a special catheter. We recommend the IUI procedure for women who plan to use donor sperm; who have not been able to conceive naturally with their partner within 1 year; if the male has mild or unexplained infertility. After consultation with the gynaecologist and the necessary examinations and tests, the IUI procedure is performed on the basis of either the natural menstrual cycle or after hormone-induced ovulation. For the male partner, semen analysis must be performed. The success of IUI depends on the woman’s age, the type of ovulation stimulation, the quality of the sperm, as well as the cause and duration of fertility issues. On average, 15% of women become pregnant with IUI. The procedure may be repeated for several consecutive months and thus the cumulative probability of pregnancy may be higher.
In traditional IVF (in vitro fertilization), the eggs and the sperm are combined in a Petri dish and the dish is cultured in an incubator with conditions similar to those in the human body. After 16–18 hours, the fertilization of the eggs is assessed and the successfully fertilized eggs are cultured further to allow for the development of embryos. Embryo development is monitored in the laboratory for 2–6 days.
ICSI (intracytoplasmic sperm injection) is a method of in vitro fertilization in which a single sperm is selected under a microscope and inserted directly into the cytoplasm of an egg using a micropipette. The ICSI method is usually used in cases of male factor infertility or if the traditional IVF method has not been successful. The use of the ICSI method is also necessary if the eggs have been previously frozen. Further development and monitoring of embryos is performed similarly to the IVF method.
The day determined for embryo transfer depends on the development of the embryos. The embryologist selects the embryo(s) of the best quality and stage of development for transfer. In Estonia, it is allowed to transfer up to 3 embryos, but it is usually recommended to transfer only 1 embryo in order to avoid the possible risks associated with multiple pregnancies. Good-quality embryos left over from transfer can be frozen. We offer the opportunity to perform a beREADY endometrial receptivity test which will help determine the most appropriate time for embryo transfer to the uterus. In the course of the embryo transfer procedure it is also possible to use EmbryoGlue. This is a transplant solution that can be used to promote the attachment of the embryo to the uterus and thus increase the likelyhood of success of the pregnancy.
To become pregnant, the embryo must attach to the inner surface of a woman’s uterus, or endometrium. Two weeks after embryo transfer, a blood test (HCG) shows whether the embryo has implanted. Clinical pregnancy can be detected beginning from 6 weeks after the transfer.