Dear patients, Next Fertility Nordic (BioEximi OÜ) is a contractual partner of the Estonian Health Insurance Fund for infertility treatment. The Health Insurance Fund reimburses infertility treatment and related visits, procedures and pregnancy detection for insured women up to and including the age of 40. The inpatient benefit does not include the initial consultation with a fertility doctor to identify the causes of infertility, or subsequent pregnancy monitoring.
Each patient is unique, and we are committed to building trusting relationships by offering individual fertility treatment solutions best suited for couples and single women. Our laboratories are equipped with the latest technology to ensure the best conditions for the culturing of gametes and embryos. We have extensive experience in freezing and preserving gametes.
During in vitro fertilisation (IVF), the fertilisation of eggs and sperm and any resulting embryo development, takes place outside of the body in special laboratory conditions. In vitro fertilisation usually requires stimulation of the ovaries before the procedure. If the sperm count of the male is normal, the eggs are fertilised using the traditional IVF method. In the case of male factor infertility, the ICSI (intracytoplasmic sperm injection) method is used. In vitro fertilisation and its success rate varies for each individual and depends on the causes of infertility. On average, approximately 30% of procedures result in a successful pregnancy.
IUI
IUI (intrauterine insemination) is a procedure where the sperm is placed into the uterus during ovulation using a special catheter.
We recommend the IUI procedure for women who:
- have not been able to conceive naturally with their partner within 1 year
- have a male partner with mild or unexplained infertility
- plan on using donor sperm
After consultation with the gynecologist and the necessary examinations and tests, the IUI procedure is performed either during the natural menstrual cycle or during a hormone-induced ovulation cycle. For the male partner, semen analysis must be performed. The success of IUI depends on the woman’s age, the type of ovulation stimulation, the quality of the sperm, as well as the cause and duration of fertility issues. On average, 15% of women become pregnant with IUI. The procedure may be repeated for several consecutive months and thus the cumulative probability of pregnancy may be higher.
IVF
In traditional IVF (in vitro fertilisation), the eggs and the sperm are combined in a Petri dish and the dish is cultured in an incubator with conditions similar to those in the human body. After 16–18 hours, the fertilisation of the eggs is assessed and the successfully fertilised eggs are cultured further to allow for the development of embryos. Embryo development is monitored in the laboratory for 2–6 days. The success of IVF varies for everyone and depends on the causes of infertility.
ICSI
ICSI (intracytoplasmic sperm injection) is a method of in vitro fertilisation in which a single sperm is selected under a microscope and inserted directly into the cytoplasm of an egg using a micropipette. The ICSI method is usually used in cases of male factor infertility or if the traditional IVF method has not been successful. The use of the ICSI method is also necessary if the eggs have been previously frozen. Further development and monitoring of embryos is performed similarly to the IVF method.
Embryo transfer
The day determined for embryo transfer depends on the development of the embryos. The embryologist selects the best quality embryo(s) at the correct stage of development for transfer. In Estonia, it is allowed by law to transfer up to 3 embryos per one procedure. Any remaining good quality embryos can be frozen. We offer the opportunity to perform a beREADY endometrial receptivity test which will help determine the most appropriate time for embryo transfer to the uterus. During the embryo transfer procedure, it is possible to opt for using EmbryoGlue. This is an additional culture medium that can promote the attachment of the embryo to the uterus and thus increase the likelihood of implantation.
Pregnancy detection
To become pregnant, the embryo must attach to the inner surface of a woman’s uterus, or endometrium. Two weeks after embryo transfer, a blood test (hCG) shows whether the embryo has implanted or not. A clinical pregnancy can usually be detected 6 weeks after the transfer using ultrasound examination.